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pentobarbital will minimize the level or influence of diazepam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Sturdy or moderate CYP3A4 inducers could raise amount of diazepam elimination; hence, efficacy of diazepam could possibly be diminished.pentobarbital and olopatadine intranasal the two maximize sed